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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e601c9fea4c7280a5fab183d24aa35439c3623eedd72d7cbec62ed480e632a2d' 
  AND token = 'cYQbBMhOkaNhw0hHiisLVAwlOKfNJ0AezOLgLH4n8Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}