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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c05640ce4f125a84a2c14d7b9a04071ef0a6a3e599aa1f241f89ff968bfd1333' 
  AND token = 'NVgEgqEWvG1cCJfvDh5uRJc6YOwJMuGnMZQut7kmCpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}