SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48cbaeaf0efa6b42f81040bacd9250f002c4813baf5aa19a4bc06320306b6632' 
  AND token = 'OsecGw2U4+XjvIphiH9oxGkt50IyVK5K3db2uWvkACk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}