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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e0380b6a4c24a9f86a85a9f39744eb1695e11d4c6c7ed5c6195a4df9b74593' 
  AND token = 'NQfm/Whe3ASFBTLJhC7XcXosSPkXpbHW5u0epu+hFY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}