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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6557f5fa631807e9226c7064a3724f85099c6dc657decb3d9ef4cd87e6ff800' 
  AND token = 'IbeqocqGI4bNzO9a//nXyObOAdu6TxTzfQPWvo38wdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}