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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c886b3d49088b878f93fb4003a5b561761f3225fd8edfa069e491395e393efb7' 
  AND token = 'qbENC7qEnB+qImosfBo7lU1UOfYNhjBk6Ln/F6BTpBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}