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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b220d7a5e551292a4674fef6c4d34746e353da66112567436dc7eda66bb86524' 
  AND token = 'lOAgQA9EQ+Z7qRaY8deemlI889f7YxWSFBUHaSXeFp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}