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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d7d4af147104efd2201ef08d163f66f1d68968ccf2041ea7bea51a6b33c0bc' 
  AND token = '64dhnbDCdKCm82YXGSwy+Zx8CEoHtESQzgAEPo3S3SU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}