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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9437407b7e4a12a71085f1e76f6341406b7014101f7cd49db030365a01e58fd6' 
  AND token = 'tZ6PP7tKl5zji5VUpMZkauADirkkMZYgAoJwNy4o9CM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}