SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eee489660b94e893d7d13673e643af770aaef2e73db2aced768d8d3c8e77d33' 
  AND token = '/7cA7dgbtTP2nbSbO3O+Vjbh+EvZHGdUDCf5hIbKw8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}