SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bed20b8b4b1a693e09c888ab6b7f292b518fd8f49d3ce3a587bfd9f9f491398' 
  AND token = 'qyiu/IGewqIlAixwY+CUKgCVFNRnT2A4MJhCsv9+mbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00089

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}