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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63521aed82a7278ddda0f00f4b9984f020c4e1bf078f044a50061f5d63124dd5' 
  AND token = 'XetvtFCBox9vgj71TZ1xnw7U348z3VmNjFbPmT9GbIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}