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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de2b4168a586e1a5a08c566f2bfb6d6ec86290d497da1b981fc178c8b40ab2ca' 
  AND token = 'QEo7ep7LWHJL8wwCoBdUwBg/GLsJzJ51a63MoziwACA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}