SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68270ffcde76f13d618013f6942fd73e2adf47798b3662d716777022848411a3' 
  AND token = 'CXoOVKw2ZtFVwqLXDA5ZTqPUrNCczznd5JLG858UJfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}