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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a25564b40ec8c7c3d8a0cd2a241410b315b6868e64aff6e75d87319c0ee6abc' 
  AND token = 'nwEp4q6xGvmf4fqOH6Vr6pN9lnP5qwy10JWGYder81s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}