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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a38bbd08d25659dbef19d60f1939f454347543ade74dc1278d153c0b9b03ca36' 
  AND token = 'QjLnt+YF8lMFskrqtLkAAJwstA6T33DnGn7WM2gbFwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}