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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '485bbf12dab99da7552e70ba2f84610004226ae39b741d70a2ac2223ea3a3272' 
  AND token = 'tKY+uH3j/t2ObnO2uu82kiT1QJRVJLACt1EcevVsQLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}