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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '106b6c09d98b1f80d6a075eb8b436e95a7bed71b022d9033b5dea0d2422053c5' 
  AND token = 'm9nl3ZxhMs7TtLej6mqvBn/Tb7sBew89eixBI3CCsAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00082

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}