SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354fb42ee6e5d160cd228fce2c4bf02bf17af768a2635620dbe01e36d7f9c7b6' 
  AND token = 'yWHM4socaEyigyme9F+XFKcKydgBGIm9+pLJeKEyRhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}