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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '396e204d5e1d67eed9d26a3f0c94235f06c0d830e8388428d7298bb89121342b' 
  AND token = 'cOd7U2YwTVba021GMVE9wDBZT06+fGLD3ora1+pjU+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}