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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea158de6e965140633df8c9c6c5ba95504eefa80d0359b965b3e1741a46408ff' 
  AND token = 'aYjw2j0ctRP2yf4/+rh2gD/9hH9kerwiytT8TjEG6Zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}