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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae6bfb99566b4b61c70d563a9d558352a20986d92b0d861cc79b92a945c76d05' 
  AND token = 'nTZT9jS6n92V2pB7pGDYb3hYLtDnypVt7ZJ2jTK0p40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}