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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a2fe7f52cc783d045febb4ef841bb21ea5176afc49ec7ee77dcf50938f6f925' 
  AND token = 'VPHR2X2eIVBpC93SRvTiv9rDPPUns7h8QRQA9qaMVYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}