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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85e1b0307af77c4de8d8c67e4352ffde50e516a0c2fb62ec9496fd00f9d3202f' 
  AND token = 'AnPX/pMnaJTwQMocfT1aqYbC4ZDleylclfvj/ndDHQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}