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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f979b491c4f94ade0559adcdf29542b7ef07a4e71a4c8e8229c9ad5130a5a8f' 
  AND token = 'oX8bkgTUUI9d+C4jbo22n15NLa9ZAwfVDBahwu9a0yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}