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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48a1dca646ffdcac1a7fbdff6e0a382d82a89c02da5c85f6fe391c7f57b1b3b8' 
  AND token = 'w0xqXv6pWwCKrHAD5LULoBxEEyVaLCJIBTAiKXVUpH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}