SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1d83c56b57bb8307dca2411b902e5596036b71ce80df302e86e2b45a7509294' 
  AND token = 'uvXrND10bSiKaUduZmKGcQWbR9s0qA97QBz25BvPFxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}