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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46aed3ff15c0035c9304e0be7b1df9d2727f2bedc02ce1062f96ab0869faa5d3' 
  AND token = 'yfesYk5fFD7kAJ47g5JQfafTRAuy6dUMqpGR/Zm7yeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}