SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '966e0eae4d1dc07a6af01dbd4e80b85e72bb381dc4a7c5496ce2755ae5d57e79' 
  AND token = '1Uvmc6T3HIKjk52O1AXH+A/geJV/YI7fgeB65OQuQmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}