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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '092d0b4137cf1023c6961c4cc2e192fbf4c002cf4e392021dd0dfed40cb9bccd' 
  AND token = 'jZzXt8B99hgmhRwuk7jyoeBMgYYfBhJM8DfUwKCY9/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}