SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd976c0d93dbf1389dae19a25cab2b8d0945e29ff475d701719f1be34813f6f16' 
  AND token = 'FDvC6f3eO1/E8lW8vhfWxWP5SiK1S08OCExhk/NHv2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}