SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f49b11a327bd2b7656dbbe479f111668395b886096451254bd4e8bd6e66f77f9' 
  AND token = '7Jg3dkvPtN8QicNwS9/QyeVYjSNUgTZ5FLmXuguFDQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}