SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2258b14633e3408047f856f6a8b8348ffbee3b44d7770e2286b4df7e38049971' 
  AND token = '9K/vlF4SuBf8fL5aUvjgzP8RLdwkAfED72caqfp9fE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}