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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aed734e9c5f10ec291f3c454f2bfe7652e4a0ab4655ca90a065af8304b52e767' 
  AND token = 'cBIO+8hoGSooyYsZQ+cxgrv3MKASw0CqmMPUefGaRUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}