SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6647d5f6298d3e3fd2fe808206fcec83f9ac7cff2ba4ca88198bdb4bdbe008f2' 
  AND token = 'zuSLfxaiICU0vFSH+xQck4u8xYoyo21aRu8mZAgw7sA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}