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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a66a29fd33311106ce723fd0a36e8149e0ceb45825a8f4142f4571008f850fa' 
  AND token = 'LUPEGC+Z8RV963CarXWladpFDmV1I39TH01jODJbEjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}