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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32e4dfa87225a10174a03b2b2f9e0b530bd26300a29f429d1f88a89b2617791c' 
  AND token = 'F6IzZa9017bwt4OgsobyiLoOucbiTxH2ROlh0CFF23U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}