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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46648d118d471da96b0361a56f3e7131d5ae88a9ca0a84dd9df583180e5d75b3' 
  AND token = 'fSha9utUev/Z0dSmDXfkJinNwHhHMFh1rdW8PHJ3z6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}