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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2b1905c1c409e16baa453b054cd2e95fa28608aa555b6eb8e9966d373dcde61' 
  AND token = '3D+YskiC1UYuRh/ibAlQQg4NXJjFviSk8AcdpuRzhgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}