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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b01c60a5023f44b10726f114fbabb4a9c47afa21c566705ae836c33692e6b175' 
  AND token = '7qEQ/OMfCrJis2rBVRUZSCoSRgrvbDo1QUymLRSoMTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}