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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ab385edd1e92c41cf108754e6b3e08b1ff6787c4646d4cc9e670f6674b30348' 
  AND token = 'YM4kqlFeN8mzkZkMoBB7aLJ5HDksrvsIe3mnnfxPbGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}