SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f024a4685a645b8415ae7c341db8c635f347455db7472714ffb6025a1f17feaf' 
  AND token = 'hgxKGTfi26+aBzflgXUFEp7KGYVpUeYIwQDU3E7Ded0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}