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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10bf584b9670aa02cb1b1231785b4cab6425fc2ffb3d70fd522e33e7eb152af3' 
  AND token = 'b50w2EtT006e/5bGn4CEwYZ8SPIDhWmoGCkII9jV8TI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}