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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b0826b1de1d3b46656588de4b9d25445ab779f0d9a0a9b299c38c3141dafd2c' 
  AND token = 'td/O14bnWynmTi+O/MCZKhoiAVnHwXqTXCC81nhWHiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}