SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d2541ceb1bdbbb086a3dc161606708b09de7d774a38c57a058f852e59bc1ea' 
  AND token = 'kWHYNRsOYz0qidbig0M6MvoWwkCOTjr12oCpnTVj7kA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}