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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '450f810d6d97b8901bf5567059dc9beb28b19d6e0eabbe68a9f50165675a91f7' 
  AND token = 'zAPrhqK0HjeOfDV4muJLij1HyJJxNSJld86EZbrnwZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}