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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d4a0cbec99d1b1af54c66e2c9b611e34563fade0aac85cfdc435621666fdc4a' 
  AND token = 'Rq1rFb7d/5VbCYUvCcqC9aCd6f5qs2NIkIBjTQrg93k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}