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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cf26f9573d002f96e49c649e694a4e84c0b2f0ab8003458ee828fe34df6894d' 
  AND token = 'nDMp0D/GGm9qp6BqxEpnuaESIC6k6kxE1qC1zFdEMRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}