SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de685b6e59da56feaee2244fd8f5798bc7db1ed2a3f76fb73b9288d08e29b756' 
  AND token = 'To72kpRNedvoR4Y38BHR6+6CgCnrUEU8SJn9n6P68Lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}