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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebf4747266887e3c2469add6d20f41bae6472caa7f9b50d204b2b617319634f5' 
  AND token = 'IA4TKCqBjvPvQuWaqfexNzKP+N4s00QhzCwcQVz1PE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}